Revisiting enigmatic cortical calretinin-expressing interneurons
نویسندگان
چکیده
منابع مشابه
Revisiting enigmatic cortical calretinin-expressing interneurons
Cortical calretinin (CR)-expressing interneurons represent a heterogeneous subpopulation of about 10-30% of GABAergic interneurons, which altogether total ca. 12-20% of all cortical neurons. In the rodent neocortex, CR cells display different somatodendritic morphologies ranging from bipolar to multipolar but the bipolar cells and their variations dominate. They are also diverse at the molecula...
متن کاملEditorial: At the top of the interneuronal pyramid—calretinin expressing cortical interneurons
(2015) Editorial: At the top of the interneuronal pyramid—calretinin expressing cortical interneurons. Intracellular protein calretinin (CR) acquired its name based on structural similarity to calbindin D28k and the site of first detection—retina (Rogers, 1987). Soon after this discovery, a basic description of the distribution of CR in rodent brain emerged from the work of several authors (rev...
متن کاملSomatostatin-Expressing Inhibitory Interneurons in Cortical Circuits
Cortical inhibitory neurons exhibit remarkable diversity in their morphology, connectivity, and synaptic properties. Here, we review the function of somatostatin-expressing (SOM) inhibitory interneurons, focusing largely on sensory cortex. SOM neurons also comprise a number of subpopulations that can be distinguished by their morphology, input and output connectivity, laminar location, firing p...
متن کاملCXCR4 is required for proper regional and laminar distribution of cortical somatostatin-, calretinin-, and neuropeptide Y-expressing GABAergic interneurons.
Cortical GABAergic interneurons are divided into various subtypes, with each subtype contributing to rich variety and fine details of inhibition. Despite the functional importance of each interneuron subtype, the molecular mechanisms that contribute to sorting them to their appropriate positions within the cortex remain unclear. Here, we show that the chemokine receptor CXCR4 regulates the regi...
متن کاملStructural and molecular heterogeneity of calretinin‐expressing interneurons in the rodent and primate striatum
Calretinin-expressing (CR+) interneurons are the most common type of striatal interneuron in primates. However, because CR+ interneurons are relatively scarce in rodent striatum, little is known about their molecular and other properties, and they are typically excluded from models of striatal circuitry. Moreover, CR+ interneurons are often treated in models as a single homogenous population, d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Neuroanatomy
سال: 2014
ISSN: 1662-5129
DOI: 10.3389/fnana.2014.00052